Learn about early diabetes symptoms, diabetic diet information, diabetes care, type 1 diabetes, insulin resistance and type 2 diabetes. Read the latest medical research on diabetes.
Scientists have identified four viruses that can produce insulin-like hormones that are active on human cells. The discovery brings new possibilities for revealing biological mechanisms that may cause diabetes or cancer.
Posted: February 19, 2018, 8:50 pm
As we are approaching the 100th anniversary of the discovery of insulin, a wide array of its signaling pathways has been defined. However, the initial step in insulin action, i.e. the engagement with its cell-surface receptor and the resulting conformational change, which propagates across the plasma membrane to the intracellular module, remains poorly understood.
Posted: February 19, 2018, 3:32 pm
A new study suggests that higher yogurt intake is associated with lower cardiovascular disease risk among hypertensive men and women.
Posted: February 15, 2018, 7:17 pm
A drug commonly used to control high blood pressure may also help prevent the onset of type 1 diabetes in up to 60 percent of those at risk for the disease.
Posted: February 15, 2018, 5:50 pm
Bone cells do not just form new bone, they also influence the blood sugar level. Scientists have now discovered a new mechanism that controls this link. The metabolism of bone cells determines how much sugar they use; if the bone cells consume more sugar than normal, this can lower the glucose level in the blood. This research may contribute to future therapies for conditions such as osteoporosis and diabetes.
Posted: February 14, 2018, 4:10 pm
For the first time it has been shown that drinking a ketone supplement can lower blood sugar levels, presenting a potential future method to control spikes in blood sugar experienced by diabetics.
Posted: February 14, 2018, 3:33 am
A drug-carrying microsphere within a cell-bearing microcapsule could be the key to transplanting insulin-secreting pig pancreas cells into human patients whose own cells have been destroyed by type I diabetes.
Posted: February 12, 2018, 5:58 pm
A new study takes a deep look at the connection between shift work and type 2 diabetes. Investigators leveraged data on hundreds of thousands of people in the UK Biobank to better understand how shift work -- especially frequent night work -- contributes to the likelihood of type 2 diabetes. The team also developed a genetic risk score for type 2 diabetes, examining genetic data for tens of thousands of workers in the database.
Posted: February 12, 2018, 5:12 pm
A new study of mice with the rodent equivalent of metabolic syndrome has added to evidence that the intestinal microbiome -- a 'garden' of bacterial, viral and fungal genes -- plays a substantial role in the development of obesity and insulin resistance in mammals, including humans.
Posted: February 12, 2018, 3:06 pm
Scientists have figured out how to control glucose levels in the bloodstream without the usual side effects of nausea, vomiting or malaise.
Posted: February 9, 2018, 10:05 pm
Scientists are enlisting the help of 'pillownauts' to push back the boundaries of space travel in a new study to examine a potentially serious adverse effect of weightlessness on the human body.
Posted: February 8, 2018, 7:44 pm
Ever wonder why obese bodies burn less calories or why dieting often leads to a plateau in weight loss? In both cases the body is trying to defend its weight by regulating energy expenditure. In a new paper, researchers identify the enzyme TANK-binding kinase 1 (TBK1) as a key player in the control of energy expenditure during both obesity and fasting.
Posted: February 8, 2018, 7:12 pm
Treating obese mice with catestatin (CST), a peptide naturally occurring in the body, showed significant improvement in glucose and insulin tolerance and reduced body weight, report researchers.
Posted: February 8, 2018, 3:42 pm
Convention was that the signaling protein, transforming growth factor-ß-activated kinase 1 (TAK1) is detrimental to muscle health since it activates pathways associated with muscle wasting. However deactivating TAK1 did not preserve muscle health as expected, but resulted in the opposite effect: muscle wasting.
Posted: February 8, 2018, 3:42 pm
Restoring levels of coenzyme Q10 (CoQ), a key molecule in energy production in cells, could overcome insulin resistance or pre-diabetes -- a precursor to type 2 diabetes and cardiovascular disease.
Posted: February 7, 2018, 4:01 pm
In a new study, researchers show why insulin secretion is not working properly in patients suffering from type-2 diabetes.
Posted: February 6, 2018, 7:07 pm
A new study shows that the same mechanisms behind the beneficial effects of exercise training on the brain also help to counteract fat and to strengthen the immune system. The results may ultimately give rise to new obesity and diabetes drugs.
Posted: February 6, 2018, 7:06 pm
Researchers have found a new way of accelerating wound healing. The technology and the mode of action involves using lactic acid bacteria as vectors to produce and deliver a human chemokine on site in the wounds. The research group is the first in the world to have developed the concept for topical use and the technology could turn out to be disruptive to the field of biologic drugs.
Posted: February 5, 2018, 9:15 pm
People with diabetes are twice as likely to develop cataract as the general population and the relative risk is highest in those aged between 45 and 54, according to a new study.
Posted: February 5, 2018, 3:27 pm
A group of compounds derived from hops can likely improve cognitive and other functions in people with metabolic syndrome.
Posted: February 5, 2018, 2:29 pm
Crash diets can cause a transient deterioration in heart function, according to new research. Patients with heart disease should seek medical advice before adopting a very low calorie diet.
Posted: February 2, 2018, 5:38 pm
You might want to read this on your feet. A new study found that standing instead of sitting for six hours a day could prevent weight gain and help people to actually lose weight.
Posted: January 31, 2018, 11:47 pm
Several common chronic diseases together account for more than a fifth of new cancer cases and more than a third of cancer deaths.
Posted: January 31, 2018, 11:47 pm
Men with type 2 diabetes are less likely to develop prostate cancer than patients without diabetes. However, the mortality rate is higher. Researchers were able to show that in the affected individuals the androgen receptor and the mitogenic forms of the insulin receptor were more strongly expressed. This could explain why patients with diabetes have a poorer prognosis for prostate cancer.
Posted: January 31, 2018, 5:13 pm
People with chronic kidney disease have much higher risk of cardiovascular disease, the leading cause of death for those with type 1 diabetes. In a new article researchers demonstrated that the eye condition known as proliferative diabetic retinopathy also is independently associated with cardiovascular disease.
Posted: January 31, 2018, 4:04 pm
A new study shows that Vitamin D3 could help restore damage to the cardiovascular system caused by diseases like hypertension and diabetes.
Posted: January 30, 2018, 7:02 pm
Scientists discovered how a gene mutation affects T cell function to promote immune disorders and then tested a treatment based on the discovery -- successfully fixing donated immune cells from a 16-year-old boy with an abnormally low level of white blood cells called lymphopenia.
Posted: January 30, 2018, 2:08 pm
A new study indicates that women who breastfeed more children, and for longer periods of time, are less likely to suffer from hypertension after they reach menopause. This is less true of obese women, however.
Posted: January 30, 2018, 2:08 pm
Researchers report a new mechanism for regulating glucose uptake by the liver which has implications for type 2 diabetes and its treatment.
Posted: January 26, 2018, 2:53 pm
· New research finds high prevalence of vitamin D deficiency in IBS patients – regardless of their ethnicity
Posted: January 25, 2018, 4:08 pm
Diabetes patients have an increased risk of suffering serious infections or death compared to the general public, new research has shown.
Posted: January 25, 2018, 4:00 pm
Constantly tracking a person's glucose levels through their tears or sweat could be one step closer to providing people with diabetes an improved monitoring tool. Researchers report the development of an ultra-thin, flexible sensor that could be incorporated into contact lenses or on the backs of watches for real-time glucose tracking.
Posted: January 24, 2018, 4:39 pm
A team of scientists has developed a microfluidic device that mimics the human blood-retinal barrier. It enables to test molecules in vitro and to study diseases such as diabetic retinopathy.
Posted: January 23, 2018, 4:25 pm
Researchers report that development of the endocrine pancreas is promoted by a weblike network of epithelial tubes that exist only transiently in the developing embryo. The findings suggest that a deeper understanding of this endocrine differentiation 'niche' could propel development of novel treatments for diabetes.
Posted: January 22, 2018, 10:55 pm
Overweight women after menopause who eat a Paleolithic diet can maintain weight loss in the long term. The levels of risk factors of type 2 diabetes and cardiovascular diseases also decrease.
Posted: January 18, 2018, 7:29 pm
In a long-term national study, breastfeeding for six months or longer cuts the risk of developing type 2 diabetes nearly in half for women throughout their childbearing years, according to new research.
Posted: January 17, 2018, 11:50 pm
The human body undergoes dramatic changes during even short periods of weight gain and loss, according to a new study.
Posted: January 17, 2018, 6:11 pm
Named after the Greek goddess who spun the thread of life, Klotho proteins play an important role in the regulation of longevity and metabolism. In a recent study, researchers revealed the three-dimensional structure of one of these proteins, beta-Klotho, illuminating its intricate mechanism and therapeutic potential.
Posted: January 17, 2018, 6:11 pm
Six novel chromosomal regions identified by scientists leading a large, prospective study of children at risk for type 1 diabetes will enable the discovery of more genes that cause the disease and more targets for treating or even preventing it.
Posted: January 17, 2018, 3:41 pm
In Switzerland, 5,500 operations to combat morbid obesity are conducted every year. Gastric bypasses and sleeve gastrectomy operations perform similarly: patients lose two-thirds of their excess weight in the long term. When it comes to gastric acid reflux, the bypass clearly shows better results.
Posted: January 17, 2018, 2:23 pm
Women who have gestational diabetes mellitus (GDM) during pregnancy have a higher than usual risk of developing type 2 diabetes, hypertension, and ischemic heart disease in the future, according to new research.
Posted: January 16, 2018, 8:14 pm
Rising obesity rates in several Southern US states are leading to a rapid increase in new cases of diabetes among both black and white adults. A new study found the risk of diabetes is double for black patients.
Posted: January 16, 2018, 4:10 pm
Massive banks of genetic information are being harnessed to shed new light on modifiable health risks that underlie common diseases. Researchers have pioneered a method to integrate data from multiple large-scale studies to assess risk factors such as body mass index (BMI) and cholesterol levels, and their association with diseases including type two diabetes and heart disease.
Posted: January 16, 2018, 2:56 pm
A study of families with rare blood sugar conditions has revealed a new gene thought to be critical in the regulation of insulin, the key hormone in diabetes.
Posted: January 15, 2018, 8:45 pm
In a new study in rats, researchers have demonstrated that is possible to restore insulin sensitivity and glucose homeostasis by modulating electrically the carotid sinus nerve, the sensitive nerve that connects the carotid body with the brain.
Posted: January 15, 2018, 2:41 pm
New research has demonstrated that an enzyme she had previously identified as playing a role in peripheral neuropathy induced by cancer chemotherapy also plays a role in peripheral neuropathy caused by diabetes. The significance of the identification of a common molecular mechanism is that the drug candidates she identified to treat chemotherapy-induced peripheral neuropathy could potentially be used to treat peripheral neuropathy caused by diabetes as well.
Posted: January 12, 2018, 2:12 pm
New research in mice and humans suggests that an enzyme called SNRK suppresses inflammation in obesity-related 'white fat' while increasing metabolism in heat-producing 'brown fat,' making SNRK an intriguing target in the battle against obesity.
Posted: January 11, 2018, 3:04 am
A new study reports that chronic exposure to arsenic interferes with insulin secretion in the pancreas, which may increase the risk of diabetes.
Posted: January 10, 2018, 9:33 pm
We may have a new reason, in addition to vitamin D generation, to bask in a little sunshine. A breakthrough has shown the fat cells that lie just beneath our skin shrink when exposed to the blue light emitted by the sun.
Posted: January 10, 2018, 4:30 pm
With new imaging methods, scientists hope to make significant progress in the fight against obesity. A new report reveals striking images of neural projections within fat tissue, and clues for the development of new drugs.
Posted: January 9, 2018, 11:50 pm
Four per cent of the Greenlandic population are, due to a specific genetic alteration, in the risk of developing obesity and diabetes, a new study concludes. The gene represent a possible treatment target, the researchers argue.
Posted: January 9, 2018, 3:28 pm
Researchers have found new evidence to suggest that longer periods of sedentary time (defined as any sitting/reclining activity with low energy expenditure) are more strongly associated with the amount of fat deposited around internal organs.
Posted: January 9, 2018, 2:18 pm
In experiments on mice, researchers have pinpointed a mechanism for the conversion of energy-storing white fat into energy-expending brown fat.
Posted: January 5, 2018, 7:26 pm
A new study finds that lipid overload in heart cells, a common feature in diabetes and obesity, leads to misshapen mitochondria that don't produce energy efficiently. This structural disruption may contribute to the two- to five-fold increased risk of heart failure in people with diabetes.
Posted: January 5, 2018, 6:52 pm
A study demonstrates that a gene therapy approach can lead to the long-term survival of functional beta cells as well as normal blood glucose levels for an extended period of time in mice with type 1 diabetes. The researchers used an adeno-associated viral (AAV) vector to deliver to the mouse pancreas two proteins, Pdx1 and MafA, which reprogrammed plentiful alpha cells into functional, insulin-producing beta cells.
Posted: January 4, 2018, 8:35 pm
Scientists have discovered a mechanism that amplifies the autoimmune reaction in an early stage of pancreatic islet autoimmunity prior to the progression to clinical type 1 diabetes. If the researchers blocked the corresponding molecules, the immune system was significantly less active.
Posted: January 4, 2018, 5:03 pm
The idea that sugar could be a fundamental cause of the global obesity and diabetes epidemics, with deleterious effects on the human body that go beyond just empty calories, should be considered seriously again, argues an expert.
Posted: January 4, 2018, 12:46 am
Although China remains one of the countries with the lowest incidence of type 1 diabetes globally, a new study shows that there has been a rapid increase in the number of new cases (incidence) of the condition in under-15s in the past two decades.
Posted: January 4, 2018, 12:46 am
For the more than 1 million Americans who live with type 1 diabetes, daily insulin injections are literally a matter of life and death. And while there is no cure, a team has developed a device that could revolutionize management of the disease.
Posted: January 2, 2018, 8:31 pm
In a surprising finding, blacks and whites have the same risk of developing diabetes when all biological factors for the disease are considered over time, reports a study. The finding flips long-held beliefs that there is an unexplained reason why blacks have double the rate of diabetes compared to whites by midlife, which is considered early onset.
Posted: January 2, 2018, 6:48 pm